Focal therapy for prostate cancer: the honest version

July 20, 2026 By Ashwin Sridhar

Almost every week now, a patient sits down having just read that there’s a prostate cancer treatment that cures you with no side effects. And they’ve half made up their mind before we’ve even started.

I understand why. Those headlines have been everywhere, and the recent UK data behind them is genuinely good news. But “cure with no side effects” is not quite what the study says. And when you’re making one of the biggest decisions of your life, you deserve the whole picture, not the headline.

So here’s what I actually tell my patients.

In the data, about a third of men needed a second round, and about a third still went on to have surgery or radiotherapy anyway. That isn’t the treatment failing. It’s just what it is. A very good way to delay, and sometimes avoid, bigger treatment. Rarely a one and done cure.

Only a small fraction of the men in the study had actually been followed that long. It doesn’t make the treatment unsafe, the early cancer control genuinely looks good, it just means the long-term proof isn’t quite there yet.

To stay on it safely, you sign up for PSA tests, MRI scans and repeat biopsies. Every one of them comes with a wait, and a bit of worry. That’s a real cost even when everything is going well, and it almost never makes the headlines.

Operating on a prostate that’s already had focal therapy is harder. The scar tissue makes it more difficult to protect the nerves that control continence and erections, and the results are often not as good as if we’d operated first. Choosing focal therapy means quietly accepting that trade.

None of this makes focal therapy a bad option. For the right man it’s a great one, and I offer it. But the honest comparison has shifted. The techniques we use now, things like Retzius-sparing surgery to protect continence, and real-time margin checks called NeuroSAFE that let us safely spare the nerves, have closed a lot of the gap that made avoiding surgery feel so urgent.

It was never focal versus surgery. It’s which one fits your cancer, your body, and the life you want to keep living. And the best thing any newly diagnosed man can do is sit down with someone who’ll talk him through all of it honestly, including the parts that don’t fit neatly into a headline.

If you or someone you love has just been diagnosed, book a consultation and we’ll go , focal therapy included, so you can choose well.

General information, not a substitute for advice from your own medical team.

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